Key result
Aerobic exercise combined with chitosan nanoparticle-encapsulated ginger significantly increased miRNA-214 expression (P<0.001) and improved cardiac fibrosis in rats with myocardial infarction.
Why the study?
Does aerobic exercise combined with chitosan nanoparticle-encapsulated ginger improve cardiac biomarkers and gene expression in a rat model of isoproterenol-induced myocardial infarction?
Does aerobic exercise combined with chitosan nanoparticle-encapsulated ginger improve cardiac biomarkers and gene expression in a rat model of isoproterenol-induced myocardial infarction?
p-value: p=<0.001
Aerobic exercise combined with chitosan nanoparticle-encapsulated ginger improves cardiac fibrosis and modulates miRNA-214, SERCA2a, and ANP expression in a rat model of myocardial infarction.
May benefit MI in rat models with exercise; hypothesis-generating and should not change practice.
What is current knowledge?Aerobic exercise combined with chitosan nanoparticle-encapsulated ginger regulated the miRNA-214 and SERCA2a in isoproterenol-induced myocardial infarction in rats. What is new here?Chitosan nanoparticle-encapsulated ginger enhanced the condition of myocardial infarction.
No takes yet. Share an insight, caveat, or question.
Fallahzadeh et al. (2023) studied Isoproterenol-induced myocardial infarction (n=30). Aerobic exercise and chitosan nanoparticle-encapsulated ginger vs. Isoproterenol (MI model without treatment) was evaluated on Expression of miRNA-214 (p=<0.001). Aerobic exercise combined with chitosan nanoparticle-encapsulated ginger significantly increased miRNA-214 expression (P<0.001) and improved cardiac fibrosis in rats with myocardial infarction.
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