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January 1, 2015Korean Journal of Family MedicineOpen Access

Health-Related Quality of Life and Cardiovascular Disease Risk in Korean Adults

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Why the study?

Is high 10-year cardiovascular disease risk associated with impaired health-related quality of life in Korean adults?

Population

10,307 Korean adults aged ≥30 years from the Fifth Korea National Health and Nutrition Examination Survey…

Comparison

High 10-year cardiovascular disease risk vs Low 10-year cardiovascular disease risk

Design

Cross-sectional

Key result

A 10-year cardiovascular disease risk of ≥20.0% was an independent predictor of impaired health-related quality of life in both men (OR 1.62) and women (OR 1.46) compared to those with low risk.

Authors

HKHyeonyoung KoJLJungkwon LeeJSJinyoung Shin

Discussion

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Overview

Supports HRQoL assessment in high-risk adults; hypothesis-generating for causal and interventional studies.

Study Design

Type

Cross-Sectional (n=10,307)

Structured PICO

Is high 10-year cardiovascular disease risk associated with impaired health-related quality of life in Korean adults?

P
Population
10,307 Korean adults aged 30 years and older without established cardiovascular disease or other major chronic illnesses, assessed for 10-year cardiovascular disease risk and health-related quality of life.
E
Exposure
High 10-year cardiovascular disease risk (Framingham risk score ≥20.0%)
C
Comparator
Low 10-year cardiovascular disease risk (Framingham risk score <10.0%)
O
Outcome
Impaired health-related quality of life (HRQoL) defined as the lowest quartile of the EuroQol-5D (EQ-5D) indexpatient reported

Main Result

Effect estimate: OR 1.62 (men), OR 1.46 (women) (95% CI 1.24-2.11 (men), 1.02-2.08 (women))

p-value: p=<0.001 (men), 0.04 (women)

High 10-year cardiovascular disease risk is independently associated with impaired health-related quality of life, particularly affecting mobility, self-care, and usual activities.

Limitations

  • Cross-sectional design precludes assessing causal relationships between 10-year CVD risk and HRQoL.
  • The EQ-5D instrument has a ceiling effect and may be less sensitive in describing mild-severity health levels.

Cite This Study

Ko et al. (2015) conducted a cross-sectional in Cardiovascular disease risk (n=10,307). High 10-year cardiovascular disease risk (≥ 20.0% Framingham risk score) vs. Low 10-year cardiovascular disease risk (< 10.0%) was evaluated on Impaired health-related quality of life (lowest quintile of the EQ-5D index score) (OR 1.62 (men), OR 1.46 (women), 95% CI 1.24-2.11 (men), 1.02-2.08 (women), p=<0.001 (men), 0.04 (women)). A 10-year cardiovascular disease risk of ≥20.0% was an independent predictor of impaired health-related quality of life in both men (OR 1.62) and women (OR 1.46) compared to those with low risk.

synapsesocial.com/papers/6a6f3bc478a11c550e08eb13https://doi.org/10.4082/kjfm.2015.36.6.349
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