Key result
Although general anaesthesia was associated with more post-operative confusion than local anaesthesia (P=0.013), surgery duration and comorbidities had a greater effect.
Why the study?
Outcomes of cochlear implant surgery under local anaesthesia with conscious sedation versus general anaesthesia in very elderly patients needed characterization in a preliminary feasibility study.
Does local anaesthesia with conscious sedation reduce post-operative confusion compared to general anaesthesia in very elderly patients undergoing cochlear implantation?
Cohort (n=44)
Does local anaesthesia with conscious sedation reduce post-operative confusion compared to general anaesthesia in very elderly patients undergoing cochlear implantation?
In very elderly patients undergoing cochlear implantation, surgery duration and patient comorbidities have a greater effect on post-operative confusion than the type of anaesthetic, although general anaesthesia was associated with higher rates of confusion.
Answers are grounded in this paper and cite their sources.
Awake LA cochlear implantation feasible in octogenarians; leaves open outcome differences versus GA in prospective trials.
Background: To characterize outcomes of very elderly patients who have had cochlear implant (CI) surgery under awake conditions with local anaesthesia (LA)/conscious sedation with patients who underwent CI surgery under general anaesthesia (GA), as a preliminary feasibility study prior to a more detailed investigation. Methods: Sixteen patients 80+ years who underwent CI under awake LA conditions were compared to 28 age-matched patients implanted under GA over an empirically chosen 2-year period 2018–2020. Results: Preoperative patient characteristics and post-operative surgical experiences were similar in both GA and LA groups. Post op confusion risk increases by 1.042-fold [odds ratio (OR) =1.042; 95% confidence interval (95% CI): 1.1 to 131.2; P=0.042] for every 1-minute increase in duration of anaesthetic. As the number of comorbidities increases there was a trend for an increased risk of cognitive impairment by almost two and half times (OR =2.4; 95% CI: 0.9 to 6.1; P=0.065). In this study GA was more likely to be associated with post operative confusion (P=0.013). Age or gender did not have a significant effect on post op confusion. Conclusions: Surgery duration and patient comorbidities has a greater effect on post-operative confusion than type of anaesthetic delivered by GA or LA. Age was not a significant factor in determining post-operative confusion. There is a high degree of variability in our study cohort as such, the results need to be interpreted with some caution.
No takes yet. Share an insight, caveat, or question.
Shah et al. (2022) conducted a cohort in cochlear implant surgery (n=44). Local anaesthesia (LA) / conscious sedation vs. General anaesthesia (GA) was evaluated on post operative confusion (p=0.013). Although general anaesthesia was associated with more post-operative confusion than local anaesthesia (P=0.013), surgery duration and comorbidities had a greater effect.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: