Key result
Computed tomography demonstrated 96% sensitivity and 85% specificity for diagnosing benign primary retroperitoneal tumours, but lacked sensitivity for assessing organ and vessel involvement.
Why the study?
Does computed tomography accurately evaluate the characteristics and organ/vessel involvement of primary retroperitoneal tumours?
Observational (n=113)
Does computed tomography accurately evaluate the characteristics and organ/vessel involvement of primary retroperitoneal tumours?
CT is useful for assessing the size and characteristics of primary retroperitoneal tumours but lacks sensitivity for assessing organ and vessel involvement.
CT may support diagnosis of benign primary retroperitoneal tumours; leaves open need for better assessment of organ and vessel involvement.
INTRODUCTION Benign and malignant primary retroperitoneal tumours (PRT) have different clinical manifestations and pathological characteristics. We explore the characteristics and evaluate the value of computed tomography (CT) for PRT. METHODS Fifty-six benign and fifty-seven malignant PRT with clinical, radiographic and surgical data were retrospectively investigated. Statistical analysis was carried out using SPSS software. RESULTS We found that mean size of benign tumours was 12.4 ± 7.7cm but 20.7 ± 11.6cm in malignant cases (P < 0.05). The accuracy of CT localisation was approximately 70%. The sensitivity and specificity of CT diagnosis for benign tumours were 96% and 85%, respectively; 51 (91%) underwent complete resection among benign cases but 42 (74%) in malignant cases (P < 0.05). Sensitivity of CT evaluation for invaded organs and vessels was 50% and 65%, respectively, and specificity was 88% and 81%, respectively. CONCLUSIONS Large size, no capsule, irregular margin, heterogeneous density and specific enhancement pattern on CT are highly suggestive of malignancy. CT is the most useful tool in assessing the size and characteristics of PRT but it does not have the sensitivity to assess the involvement of organs and vessels.
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Cheng et al. (2016) conducted an observational in Primary retroperitoneal tumours (n=113). Computed tomography (CT) was evaluated on Sensitivity and specificity of CT diagnosis for benign tumours. Computed tomography demonstrated 96% sensitivity and 85% specificity for diagnosing benign primary retroperitoneal tumours, but lacked sensitivity for assessing organ and vessel involvement.
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