Generation of average mass values and end group information of polymers by means of a combination of matrix-assisted laser desorption/ionization-mass spectrometry and liquid secondary ion-tandem mass spectrometry

Matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) and liquid secondary ion-tandem mass spectrometry (LSI-MS/MS) have been applied to the analysis of synthetic polymers to generate values for the average mass and the mass of the end groups. The average mass values were calculated for polymethylmethacrylate and polystyrene standards from the MALDI-MS data. Abundant fragment ions of the polymers, generated by means of LSI-MS/MS, were consistent with the known structures of the end groups of the polymers. Furthermore, losses from the side chains of the polymers were also observed in the LSI-MS/MS spectra.