Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 15, 1993Proceedings of the National Academy of SciencesOpen Access

Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system.

View Full Paper
Ask AI
Bookmark
Share

Authors

LWLuke WhitesellUniversity of TorontoDGDaniel A. GeselowitzNational Institutes of HealthCCChristine ChavanyMilagen (United States)

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Whitesell et al. (1993) studied this question.

synapsesocial.com/papers/6a6f4d1cf44fa9f079dcb975https://doi.org/10.1073/pnas.90.10.4665
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 13,4‐Dihydroxyphenylethylamine and 5‐Hydroxytryptamine Metabolism in the Rat: Acidic Metabolites in Cisternal Cerebrospinal Fluid Before and After Giving Probenecid1985 · 17 citations
  2. 2Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice.1991 · 564 citations
  3. 3In Vivo Modulation of N- myc Expression by Continuous Perfusion with an Antisense Oligonucleotide1991 · 58 citations
  4. 4Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.1989 · 263 citations