Key result
Group exercise was the most cost-effective depression intervention for individuals with coronary artery disease at 8 weeks (€526 per remission), followed by pharmacotherapy (€589).
Why the study?
A substantial proportion of individuals with coronary artery disease experience moderate or severe acute depression requiring treatment, but the cost-effectiveness of depression interventions in this population was unknown.
Are pharmacotherapy, psychotherapy, collaborative care, or exercise cost-effective for treating depression in individuals with coronary artery disease compared to usual care?
Population
Individuals with coronary artery disease and moderate or severe acute depression
Comparison
Pharmacotherapy, psychotherapy, collaborative care, and exercise vs usual care
Design
Cost-effectiveness analysis based on a network meta-analysis
Follow-up
8 and 26 weeks
Authors
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Group exercise may be most cost-effective for CAD-related depression at 8 weeks; hypothesis-generating, requiring prospective trials before practice change.
Are pharmacotherapy, psychotherapy, collaborative care, or exercise cost-effective for treating depression in individuals with coronary artery disease compared to usual care?
Group exercise and pharmacotherapy appear to be the most cost-effective interventions for treating depression in patients with coronary artery disease at 8 weeks.
Jabakhanji et al. (2022) studied Coronary artery disease with moderate or severe acute depression. Depression interventions (pharmacotherapy, psychotherapy, collaborative care, and exercise) vs. Usual care was evaluated on Incremental cost-effectiveness ratio (ICER) per remission. Group exercise was the most cost-effective depression intervention for individuals with coronary artery disease at 8 weeks (€526 per remission), followed by pharmacotherapy (€589).
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