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Injection of synthetic salmon calcitonin (25 mU) stimulated a decrease in the plasma calcium levels in young intact lizards, Sauromalus obesus. The same dose of synthetic salmon calcitonin had no effect on older intact lizards. A dose twice the original also had no effect in older intact lizards. This indicates an age-dependent response.
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Loren Kline (1982) studied this question.
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