Key result
Adipose tissue adipokines drive obesity-related cardiovascular disease, highlighting viable targets for therapeutic intervention.
Overweight and obesity in many countries have developed into a serious health problem by themselves and by their impact on other pathologies such as insulin resistance, type 2 diabetes, hypertension, heart disease and cancer. The modulation of these diseases by adipose tissue-derived biomolecules, so-called adipokines, could be the key to differentiate between metabolically healthy and unhealthy obesity. This review will discuss the pathophysiological role of selected adipokines, primarily focusing on cardiovascular diseases. Furthermore, we will highlight possible therapeutic approaches, which target these biomolecules.
No takes yet. Share an insight, caveat, or question.
Rega‐Kaun et al. (2013) conducted a review in Cardiovascular disease and obesity. Adipokines was evaluated. Adipose tissue-derived adipokines play a pathophysiological role in cardiovascular diseases and represent potential therapeutic targets for managing obesity-related pathologies.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: