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April 1, 1983Journal of VirologyOpen Access

Identification of an exposed region of the immunogenic capsid polypeptide VP1 on foot-and-mouth disease virus

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Population

Foot-and-mouth disease virus (serotypes A12 and O1)

Design

Preclinical

Authors

BRBetty H. RobertsonDMD. M. MooreMGMarvin J. Grubman

Discussion

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Overview

May guide FMDV vaccine epitope selection; hypothesis-generating for protective efficacy in livestock.

Structured PICO

P
Population
Foot-and-mouth disease virus (serotypes A12 and O1)
I
Intervention
Iodination, protease cleavage, and sequence analysis
O
Outcome
Identification of the exposed antigenic region of VP1

Identifies the exposed antigenic region of the foot-and-mouth disease virus VP1 capsid polypeptide, which may inform vaccine development.

Cite This Study

Robertson et al. (1983) studied this question.

synapsesocial.com/papers/6a6f5643ac440176ef280782https://doi.org/10.1128/jvi.46.1.311-316.1983
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