Foot and mouth disease (FMD) is a contagious viral disease for cloven-hoofed animals. An FMD outbreak can cause devastating economic damages, particularly in a region where FMD is not endemic. There are seven immunologically distinct serotypes of the FMD virus. Based on the differences in VP1 sequences, serotypes have been further divided into several genotypes. Although FMD vaccines play an important role in the world to control FMD, because of the broad antigenic diversity of FMDV, it is important to estimate the antigenic match between the vaccine and field virus.
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Kazuki Morioka (2023) studied this question.
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