The PanAsia strain of foot-and-mouth disease virus serotype O emerged in India and spread explosively throughout southern Asia, the Middle East, Europe, and South Africa between 1998 and 2001.
Observational (n=339)
A particular genetic lineage of foot-and-mouth disease virus (FMDV) serotype O, which we have named the PanAsia strain, was responsible for an explosive pandemic in Asia and extended to parts of Africa and Europe from 1998 to 2001. In 2000 and 2001, this virus strain caused outbreaks in the Republic of Korea, Japan, Russia, Mongolia, South Africa, the United Kingdom, Republic of Ireland, France, and the Netherlands, countries which last experienced FMD outbreaks decades before (ranging from 1934 for Korea to 1984 for the Netherlands). Although the virus has been controlled in all of these normally FMD-free or sporadically infected countries, it appears to be established throughout much of southern Asia, with geographically separated lineages evolving independently. A pandemic such as this is a rare phenomenon but demonstrates the ability of newly emerging FMDV strains to spread rapidly throughout a wide region and invade countries previously free from the disease.
Knowles et al. (Thu,) conducted a observational in Foot-and-Mouth Disease (n=339). PanAsia strain of FMDV vs. Other FMDV strains was evaluated on Phylogenetic relationships and genetic variability of the VP1 gene. The PanAsia strain of foot-and-mouth disease virus serotype O emerged in India and spread explosively throughout southern Asia, the Middle East, Europe, and South Africa between 1998 and 2001.