Key result
A 22-year-old male military trainee presented with atypical papulovesicular lesions suggestive of hand, foot, and mouth disease without oral lesions.
Case Report (n=1)
No
Coxsackievirus A6 can cause outbreaks of hand, foot, and mouth disease with atypical skin manifestations among young adults in close-contact environments like military training.
May prompt consideration of atypical HFMD in young adults; extends clinical spectrum but leaves open questions on prevalence.
On July 7, 2015, a man aged 22 years reported to sick call during basic military training at Lackland Air Force Base (AFB), Texas. He had erythematous, crusted papulovesicular lesions on the extensor surfaces of the upper and lower extremities. The patient was afebrile and otherwise well, and was evaluated later that day by the dermatology service. A viral infection was considered most likely because of the patient's age, absence of fever or constitutional symptoms, and the distribution and morphology of the lesions. The initial differential diagnosis included Henoch-Schönlein purpura, parvovirus B19, and Rocky Mountain spotted fever. However, the clinical signs, including the unique morphology and distribution of grouped vesicles and papules was suggestive of hand, foot, and mouth disease (HFMD), although the patient did not have oral lesions and reported no contact with another person with HFMD. A viral culture and punch biopsy of one of the lesions were obtained.
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Banta et al. (2016) conducted a case report in Hand, Foot, and Mouth Disease (n=1). A 22-year-old male military trainee presented with atypical papulovesicular lesions suggestive of hand, foot, and mouth disease without oral lesions.
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