Key result
Inactivated enterovirus 71 vaccines demonstrate high protective efficacy in Phase 3 trials.
This review outlines the significant progress in developing vaccines against Enterovirus 71, which is crucial for preventing outbreaks of severe nonpolio enterovirus infections.
This review summarizes the material on the development of vaccines against (nonpolio) enterovirus infection in Russia and abroad. Described the developed vaccine types, their characteristics and the results of clinical and epidemiological trials, created in China inactivated vaccines. I’is considered the possibility of creating a mucosal vaccines and vaccinal prevention strategies.
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Yagovkin et al. (2016) conducted a review in Enterovirus 71 infection. Enterovirus 71 vaccines was evaluated. Enterovirus 71 vaccines, specifically formalin-inactivated whole-virion vaccines developed in China, have demonstrated high efficacy in Phase 3 clinical trials.
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