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December 1, 1992Pacing and Clinical Electrophysiology

Observations on the Epicardial Activation of the Normal Human Heart

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Population

18 subjects undergoing surgery for Wolff-Parkinson-White syndrome, recorded during nonpreexcited sinus…

Design

Case_series

Authors

CPCarl F. PieperAPAntonio Pacifico

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Overview

Should not alter mapping strategies yet; hypothesis-generating for transmural activation patterns in larger cohorts.

Structured PICO

P
Population
18 subjects undergoing surgery for Wolff-Parkinson-White syndrome, recorded during nonpreexcited sinus rhythm, with no evidence of coronary artery disease and normal 12-lead ECG except during preexcitation or tachycardia.
I
Intervention
Multichannel computer mapping using a 119 site sock array during surgery
O
Outcome
Number, location, and timing of epicardial breakthrough (EBT) sitessurrogate

High-resolution multichannel mapping of the human heart reveals a complex mosaic of epicardial activation with multiple breakthrough sites, consistent with endocardially initiated transmural activation.

Cite This Study

Pieper et al. (1992) studied this question.

synapsesocial.com/papers/6a6f598726770c2b8ddff213https://doi.org/10.1111/j.1540-8159.1992.tb04173.x
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