Newborn identical twin boys had thrombocytopenia, leukopenia, and hepatosplenomegaly. Platelet transfusions were ineffective. Screening for infections was negative. Bone marrow aspiration showed a single hemophagocytic histiocyte. Despite medical management, the patients' condition continued to worsen. A diagnostic procedure was performed.
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Lipton et al. (2004) studied this question.
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