Effects of Measles, Gamma-Globulin-Modified Measles and Vaccine Measles on the Tuberculin Test

THAT the tuberculin test can become negative with measles has been known since the report of Pirquet1 in 1908. At that time he gave credit to Preisich, in Budapest, who had found in November, 1907, that measles caused a negative tuberculin reaction. Pirquet,2 in 1911, stated that in the first days of the eruption, the tuberculin reaction always "disappears" and reappeared only after a week. Textbooks3 note "anergy" to tuberculin in measles, but an absolute negative reaction to tuberculin in measles has not been reported. In fact Grüner,4 in 1909, using subcutaneous tuberculin tests, showed that larger doses of Old . . .