The analysis of protein-protein interactions has the growing importance in modern proteomics. It is caused by necessity of in-depth functional study of proteins which, as a rule, operate in living systems due to each other interaction in the stable or dynamic protein complexes. In this review, the brief description and a comparative evaluation of most frequently used approaches in existing variety of protein interactomics methods are given.
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As et al. (2011) studied this question.
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