April 12, 2019European Heart Journal - Cardiovascular Imaging
Fast manual long-axis strain assessment provides optimized cardiovascular event prediction following myocardial infarction
Why the study?
CMR-FT GLS provides incremental prognostic value after AMI but requires substantial post-processing, whereas manual global long-axis strain can be easily assessed from standard SSFP images.
Does manual global long-axis strain (LAS) assessment from CMR improve prediction of major adverse clinical events in patients following acute myocardial infarction compared to established parameters?
Population
1235 patients with myocardial infarction after primary PCI across eight centres in Germany
Comparison
Prognostic value of manual global long-axis strain assessment
Design
Multicentre cohort study with blinded core-laboratory assessment
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
LAS may aid simple post-AMI risk stratification; leaves open whether it replaces CMR-FT GLS in practice.
Structured PICO
Does manual global long-axis strain (LAS) assessment from CMR improve prediction of major adverse clinical events in patients following acute myocardial infarction compared to established parameters?
P
Population
1235 patients with acute myocardial infarction (795 STEMI, 440 NSTEMI) who underwent cardiovascular magnetic resonance imaging after primary percutaneous coronary intervention across eight centres in Germany.
I
Intervention
Manual global long-axis strain (LAS) assessment from standard steady state free precession CMR images.
C
Comparator
Left ventricular ejection fraction (LVEF), established clinical and imaging parameters, and CMR feature tracking global longitudinal strain (CMR-FT GLS).
O
Outcome
Major adverse clinical events (MACE) including death, reinfarction, and congestive heart failure within 1 year after AMI.composite
Manual long-axis strain assessment from standard CMR images provides a fast, software-independent method that offers incremental prognostic value for predicting MACE after acute myocardial infarction beyond LVEF.
Cite This Study
Schuster et al. (2019) studied this question.