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Under the inhibition of Cu +2 ‐induced LDL oxidation‐guided fractionation, two new flavone glycosides with galloyl substitution were isolated from the dried fallen leaves of Terminalia catappa L. Their structures were established as apigenin 6‐ C ‐(2″‐ O ‐galloyl)‐β‐ D ‐glucopyranoside ( 1 ) and apigenin 8‐ C ‐(2″‐ O ‐galloyl)‐β‐ D ‐glucopyranoside ( 2 ), together with four known flavone glycosides, isovitexin, vitexin, isoorientin, and rutin, on the basis of spectroscopic method. Compounds 1 and 2 showed significant antioxidative effects. Their IC 50 were 2.1 and 4.5 μM, respectively.
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Lin et al. (2000) studied this question.
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