The early days of liver transplantation were exciting, demanding, subject to terrible disappointments and sadness but occasional elation, and a gradual understanding of the factors necessary to achieve a satisfactory operation. In addition, care of an extremely sick patient, the management of the disease, especially if it was infectious or malignant, and the support of the relatives and the transplant team, required a group of loyal, dedicated and above all optimistic members who could see through the repeated unhappy outcomes that eventually most of the problems would be solved. This in fact has come to pass.
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R. Y. Calne (2008) studied this question.
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