Since the earliest attempts at human liver transplantation,1 research in experimental animals has had an important and intimate relationship with clinical practice.2–4 Evidence obtained in animals has been transferred to the clinics and problems encountered in the patients have been taken back to animals for clarification.5 In this review we describe examples of this flux, as well as the development of operative techniques and the significance of team construction in the laboratory as a preparatory step for clinical practice.
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Todo et al. (1985) studied this question.
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