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BEEN a recent increase in interest T in methods for delivering antitumor agents in high doses to localized areas of the body. Arterial perfusion through isolated body segments has been used with some success,1 and arterial infusion, as used by Sullivan et aL4 has also shown promise. Because of our interest in lymphangiography,296 and the technical availability of a new avenue for drug delivery, we decided to attempt to treat local malignant neoplastic masses by the intralymphatic injection of chemotherapeutic agents. The results of our preliminary work with this method are presented here.
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Jackson et al. (1962) studied this question.
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