Correcting heart rate variability for heart rate in pediatric populations is important as it alters the observed relationship between HRV, age, and sex.
HRV assessment in children warrants heart rate adjustment; challenges prior unadjusted age trends and leaves open standardization needs.
Furthermore, the increase of HRV during childhood demonstrated the same uniform pattern of the power spectra without an additional increase in the HF to LF ratio after age three years (Figure Contrary to most previous studies, Herzig D, et al. found no increase of standard HRV parameters with age in children; however, when adjusted for heart rate, there was a significant decrease of HRV parameters with increasing age Plaza-Florido A, et al. also proposed HRV correction for heart rate and the parameters became independent on both sex and heart rate, and only poorly dependent on age
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Buchhorn et al. (2019) studied this question.
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