Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 1988Journal of Clinical InvestigationOpen Access

Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy chain.

View Full Paper
Ask AI
Bookmark
Share

Authors

PFPaul FosterUniversity of BirminghamCFCA FulcherUniversity of Southern CaliforniaRHR A HoughtenUniversity of Geneva

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Foster et al. (1988) studied this question.

synapsesocial.com/papers/6a6f7819fe4101aa97dfcb06https://doi.org/10.1172/jci113559
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity.1986 · 490 citations
  2. 2Specificity of Monoclonal Antibodies to Factor VIII: C1985 · 9 citations
  3. 3Activation of factor X by factors IXa and VIII; a specific assay for factor IXa in the presence of thrombin-activated factor VIII1978 · 88 citations
  4. 4Monoclonal antibodies to porcine factor VIII coagulant and their use in the isolation of active coagulant protein1982 · 12 citations