Why the study?
Does pharmacist-managed anticoagulation reduce thromboembolic and bleeding events compared to usual care in patients requiring anticoagulation?
Does pharmacist-managed anticoagulation reduce thromboembolic and bleeding events compared to usual care in patients requiring anticoagulation?
Implementation of pharmacist-managed anticoagulation clinics across a health system improves clinical outcomes by reducing thromboembolic and minor bleeding events compared to usual care.
Supports pharmacist anticoagulation services in health systems; leaves open need for randomized confirmation before practice change.
PURPOSE: A methodological approach was developed to facilitate expansion of clinical pharmacist-managed anticoagulation services across an integrated health care delivery network. METHODS: A stepwise approach to the development and implementation of ambulatory care clinical pharmacy services was used to facilitate expansion of pharmacist-managed anticoagulation clinics in a university hospital setting and a community hospital within the same health network. RESULTS: The Health Alliance of Greater Cincinnati successfully created a care delivery model using clinical pharmacists to provide comprehensive anticoagulation management services at a university hospital and a community hospital. The incidence of thromboembolic events was significantly lower in the pharmacy anticoagulation service patients versus the patients in the usual care setting (p=0.005). A statistically significant decrease in minor bleeding events was observed in the pharmacist-managed group (p=0.038). Although a decrease in major bleeding events was observed, it was not statistically significant (p=0.075). International Normalized Ratio values of the patients managed by the pharmacy anticoagulation clinics were within the therapeutic range approximately 75% of the time. CONCLUSION: A stepwise approach to the development and implementation of ambulatory care clinical pharmacy services has facilitated the expansion of pharmacist-managed anticoagulation clinics across an integrated health system. This may serve as a valuable template for other systems as they strive to develop medication therapy management services.
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Epplen et al. (2007) studied this question.
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