Why the study?
Are C10orf27 gene polymorphisms associated with multiple sclerosis susceptibility and progression?
Population
571 patients with multiple sclerosis (relapsing remitting and primary progressive) and healthy controls
Comparison
Analysis of two intronic and a non-synonymous… vs Healthy controls
Design
Case-control
Authors
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C10orf27 polymorphisms warrant further study in MS; hypothesis-generating and should not yet influence clinical decisions.
Are C10orf27 gene polymorphisms associated with multiple sclerosis susceptibility and progression?
C10orf27 gene polymorphisms are associated with multiple sclerosis susceptibility and progression, suggesting it as a candidate gene for MS pathogenesis.
Goertsches et al. (2008) studied this question.
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