Studies in Mediterranean (Cooley’s) Anemia

THE WIDESPREAD INCIDENCE of Mediterranean anemia beyond the original geographic and racial confines has resulted in a growing interest in problems of management. In locations such as the New York metropolitan area, with large concentrations of genetically susceptible persons of Italian and Greek origin, 1 the establishment of clear-cut criteria for splenectomy represents a recurring challenge when frequently repeated transfusions fail to support adequate hemoglobin levels.