Sulfanilamide and Meningitis

Article1 October 1939SULFANILAMIDE AND MENINGITISS. W. SAPPINGTON, M.D., F.A.C.P., GRANT O. FAVORITE, M.D., F.A.C.P.S. W. SAPPINGTON, M.D., F.A.C.P.Search for more papers by this author, GRANT O. FAVORITE, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-4-576 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe therapy of infections has developed almost exclusively along the lines of specificity, and an excellent example of this is the use of the many types of anti-serum for the treatment of pneumococcus pneumonia. Likewise in drug therapy, the real successes have been mostly specific in their application. Used at first as a specific in beta hemolytic streptococcus infections, the therapeutic trial of sulfanilamide and its derivatives has been extended clinically and experimentally to cover the most remarkable variety of infections. This list includes such dissimilar organisms as gram positive and negative micrococci, aerobic and anaerobic bacilli, acid fast bacilli,...References1. GAYCLARK FPAR: On the mode of action of sulfanilamide in experimental streptococcus empyema, Jr. Exper. Med., 1937, lxvi, 535. CrossrefGoogle Scholar2. BLISSLONG EAPH: Observations on the mode of action of sulfanilamide, Jr. Am. Med. Assoc., 1937, cix, 1524. CrossrefGoogle Scholar3. OSGOOD EE: Culture of human marrow. Studies on the mode of action of sulfanilamide, Jr. Am. Med. Assoc., 1938, cx, 349. CrossrefGoogle Scholar4. TRIPOLI CJ: Bacterial meningitis, Jr. Am. Med. Assoc., 1936, cvi, 171. CrossrefGoogle Scholar5. GRAY HJ: Streptococcic meningitis, Jr. Am. Med. Assoc., 1935, cv, 92. 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Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication June 25, 1938.From the Department of Pathology, Hahnemann Medical College and Hospital, Philadelphia.We wish to thank the Staffs of Hahnemann, St. Luke's and West Jersey Hospital for permitting us to treat these cases.The sulfanilamide used was kindly furnished by the Abbott Laboratories and the Winthrop Chemical Co. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byType 19 Pneumococcal Meningitis: A Patient With 75-Year Clinical and Serologic Follow Up, With a Review of the Evolution of Therapy From Antiserum to Sulfonamides to PenicillinModern Medicine and the Twentieth Century Decline in Mortality: Evidence on the Impact of Sulfa DrugsScientific Evidence versus Therapeutic Demand: The Introduction of the Sulfonamides RevisitedBarron H. Lerner, MDSTREPTOCOCCIC VIRIDANS MENINGITIS: A REVIEW OF THE LITERATURE AND REPORT OF NINE RECOVERIES*ARCHIBALD L. HOYNE, M.D., F.A.C.P., HERBERT HERZON, M.D.Treatment of influenzal meningitis with anti-influenzalrabbit serum and sulfapyridineAdvances in treatment of meningitisInfluenzal meningitis 1 October 1939Volume 13, Issue 4Page: 576-597KeywordsDrug therapyMeningitisPneumococcusPneumoniaSpecificityStreptococcal infectionsStreptococcus ePublished: 1 December 2008 Issue Published: 1 October 1939 PDF downloadLoading ...