Why the study?
Is prefrontal cortex activation associated with dyspnea during methacholine bronchial provocation tests in patients with bronchial asthma?
Is prefrontal cortex activation associated with dyspnea during methacholine bronchial provocation tests in patients with bronchial asthma?
Prefrontal cortex activation, as measured by changes in cortical oxy-Hb concentration, is significantly correlated with the intensity of dyspnea in asthma patients during methacholine provocation.
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May link dyspnea to cortical oxygenation in asthma; hypothesis-generating and requires validation before clinical use.
Fig. Correlation between peak dyspnea intensity (Borg scale) and the maximum change of cortical oxy-Hb concentration (Doxy-Hb) in patients with asthma.Doxy-Hb significantly correlated with peak dyspnea intensities (Borg scale) in asthmatics (r ¼ 0.734, p < 0.01).
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Higashimoto et al. (2020) studied this question.
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