Answers are grounded in this paper and cite their sources.
Sp1-like family is an expanding transcription factor family. Members of this family bind to the GC-box or GT-box elements in the promoter/enhancers and regulate the expression of the target genes. Currently, this family consists of at least nine members, which may act as a transactivator or a repressor on target promoters. Sp1-like transcription factors are expressed during development of vertebrate embryos in ubiquitous or tissue-specific manners and play various roles in embryonic development. This review mainly summarises their expression patterns and functions during vertebrate embryogenesis.
No takes yet. Share an insight, caveat, or question.
Zhao et al. (2005) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: