Wavelength Dependence of Inactivation and Mutation Induction to 6‐thioguanine‐resistance in V79 Chinese Hamster Fibroblasts

The wavelength dependence of inactivation and mutation induction to 6‐thioguanine‐resistance in the range between 254 and 313 nm was investigated in V79 Chinese hamster fibroblasts. The action spectra agreed quite well with those reported by others for different effects on mammalian cells. There was no distinct difference between the wavelength dependencies of inactivation and mutation induction; the ratio of mutagenic to lethal action remained constant.