Key result
Prior stroke in older adults carries a ~9% risk of incident dementia at 15 months.
Cohort (n=115)
BACKGROUND AND PURPOSE: Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS: As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at 3 and 15 months with a detailed neuropsychological evaluation (including memory, attention, executive performance, and language). RESULTS: we found that 9% of older stroke patients developed incident dementia, with significant deterioration in global cognition, memory, and attention. Only the severity of expressive language performance at 3 months was associated with dementia at follow-up. Conversely, 57 patients (50%) experienced some improvement in global cognition. None of the criteria for early cognitive impairment identified people at increased risk for dementia. CONCLUSIONS: Delayed dementia is frequent in older stoke patients, but current criteria for early cognitive impairment are not useful as predictors of cognitive deterioration. Improvement in cognition occurred in most patients.
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Ballard et al. (2003) conducted a cohort in Stroke (n=115). Prior stroke was evaluated on Incident dementia. Prior stroke in adults over 75 without baseline dementia resulted in a 9% rate of incident dementia at 15 months, although 50% experienced cognitive improvement.
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