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April 5, 2005Journal of Biological ChemistryOpen Access

A Hairpin-like Structure within an AU-rich mRNA-destabilizing Element Regulates trans-Factor Binding Selectivity and mRNA Decay Kinetics

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Authors

EFElizabeth J. FialcowitzUniversity of Maryland, BaltimoreBBBrandy Y. BrewerUniversity of Maryland, BaltimoreBKBridget P. KeenanUniversity of California, San Francisco

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Fialcowitz et al. (2005) studied this question.

synapsesocial.com/papers/6a6fb34efebe604dd7088fbfhttps://doi.org/10.1074/jbc.m500618200
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Also Consider

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  1. 1Coulombic Forces in Protein−RNA Interactions: Binding and Cleavage by Ribonuclease A and Variants at Lys7, Arg10, and Lys661998 · 58 citations
  2. 2Adhesion-Dependent Regulation of an A+U-Rich Element-Binding Activity Associated with AUF11997 · 144 citations
  3. 3Selective Degradation of AU-Rich mRNAs Promoted by the p37 AUF1 Protein Isoform2003 · 139 citations
  4. 4mRNA Openers and Closers: Modulating AU‐Rich Element‐Controlled mRNA Stability by a Molecular Switch in mRNA Secondary Structure2004 · 138 citations
  5. 5AUF1 Binding Affinity to A+U-rich Elements Correlates with Rapid mRNA Degradation1996 · 263 citations