This paper provides a historical overview of the challenges surrounding the development of a rotavirus vaccine.
Rotavirus vaccine history cautions against assuming straightforward success in new candidates; leaves open optimization for equitable global access.
Rotavirus is the most important cause of gastroenteritis worldwide. In developing countries, the virus is a major cause of death in infants and young children. In the United States, before the licensure of vaccines, rotavirus infections accounted for ∼2.7 million cases of gastroenteritis annually. Here are described the history and challenges surrounding the development of a rotavirus vaccine.
No takes yet. Share an insight, caveat, or question.
Paul A. Offit (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: