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To investigate and characterize two distinct types of calf rotavirus particles based on their density and morphology.

Characterization of Two Particle Types of Calf Rotavirus

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To investigate and characterize two distinct types of calf rotavirus particles based on their density and morphology.
Two types of rotavirus particles were isolated using caesium chloride density gradients.
Particle measurements included density as well as diameter and polypeptide composition analysis.
Morphological differences were assessed using microscopy.
The higher density particle measured 55 nm in diameter, while the lower density particle measured 66 nm.
Infectivity was linked to the larger particle, which contained one additional polypeptide.
Intermediate forms between the two types were also observed, suggesting a spectrum of rotavirus morphologies.

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Randomized trial identifies distinct rotavirus particle types with different infectivity in calves, implying unique biological roles.

Bridger et al. (1976) studied this question.

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