Catalytic functionalization of low reactive C(sp ³ )–H and C(sp ² )–H bonds of alkanes and arenes by carbene transfer from diazo compounds

The direct functionalization of low reactive C(sp(3))-H and C(sp(2))-H bonds of alkanes and arenes, respectively, by metal-induced carbene transfer from diazo compounds is reviewed. To date, this methodology has enabled the incorporation of CR(1)R(2) moieties from N2[double bond, length as m-dash]CR(1)R(2) in a chemo, regio, enantio or diastereoselective manner in those substrates with the appropriate selection of metal and ligands.