Aprevious publication (Kane, McFadzean, Squires, King, and Nicol, 1961) gave the possible reasons for the failure of metronidazole to eradicate Trichomonas vaginalis from a small percentage of treated patients. Evidence was obtained (Kane, McFadzean, and Squires, 1961) that a number of failures could be due to defective absorption of the compound. The results of investigating another possibility, namely, resist- ance of the parasite to the compound, are now presented.
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Squires et al. (1962) studied this question.
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