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November 3, 2007Applied and Environmental Microbiology

Effects of UV Radiation on Photolyase and Implications with Regards to Photoreactivation following Low- and Medium-Pressure UV Disinfection

Jiangyong Hu Puay Hoon Quek

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Abstract

Photolyase activity following exposure to low-pressure (LP) and medium-pressure (MP) UV lamps was evaluated. MP UV irradiation resulted in a greater reduction in photolyase activity than LP UV radiation. The results suggest that oxidation of the flavin adenine dinucleotide in photolyase may have caused the decrease in activity.

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Hu et al. (2007) studied this question.

synapsesocial.com/papers/6a6fc237af0c21e93927bf09 https://doi.org/10.1128/aem.00013-07

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Standardization of Methods for Fluence (UV Dose) Determination in Bench-Scale UV ExperimentsReview · 2003 · 1,216 citations
2Identification of oligothymidylates as new simple substrates for E. coli DNA photolyase and their use in a rapid spectrophotometric enzyme assayOriginal Research · 1985 · 76 citations
3Analysis of the Role of Intraprotein Electron Transfer in Photoreactivation by DNA Photolyase <i>in Vivo</i>Original Research · 2004 · 84 citations
4Evidence of Powerful Substrate Electric Fields in DNA Photolyase: Implications for Thymidine Dimer RepairOriginal Research · 2001 · 40 citations
5Determination of Pyrimidine Dimers in <i>Escherichia coli</i> and <i>Cryptosporidium parvum</i> during UV Light Inactivation, Photoreactivation, and Dark RepairOriginal Research · 2001 · 182 citations

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