What question did this study set out to answer?

Determine the existence of distinct molecular forms of UDPG-α-glucan transglucosylase and characterize the mechanisms governing their interconversion in skeletal muscle tissue.

January 1, 1964Biochemistry

Studies on UDPG-α-glucan Transglucosylase. V. Two Forms of the Enzyme in Dog Skeletal Muscle and Their Interconversion*

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Authors

MRM Rosell-PérezUniversitat de Barcelona JLJoseph LarnerUniversity of Virginia Health System

Discussion

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Implication

Biochemical analysis demonstrates two distinct forms of UDPG-α-glucan transglucosylase in canine skeletal muscle, indicating reversible interconversion mechanisms in glycogen synthesis.

Key Points

Determine the existence of distinct molecular forms of UDPG-α-glucan transglucosylase and characterize the mechanisms governing their interconversion in skeletal muscle tissue.
Extracted and fractionated UDPG-α-glucan transglucosylase from dog skeletal muscle preparations.
Assayed enzyme activity across various fractions to examine kinetic behavior and interconversion between forms.
Identified two distinct forms of UDPG-α-glucan transglucosylase in canine skeletal muscle displaying differing regulatory profiles.
Demonstrated enzymatic interconversion between the two states, establishing a dynamic biochemical switch for regulating muscle glycogen synthesis.

Cite This Study

Rosell-Pérez et al. (1964) studied this question.

synapsesocial.com/papers/6a6fc7898031ec7bb1dbf1ad https://doi.org/10.1021/bi00889a014

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January 1, 1964Biochemistry

Studies on UDPG-α-glucan Transglucosylase. V. Two Forms of the Enzyme in Dog Skeletal Muscle and Their Interconversion*

View Full Paper

Ask AI

Bookmark

Authors

MRM Rosell-PérezUniversitat de Barcelona JLJoseph LarnerUniversity of Virginia Health System

Discussion

Member takes

Implication

Biochemical analysis demonstrates two distinct forms of UDPG-α-glucan transglucosylase in canine skeletal muscle, indicating reversible interconversion mechanisms in glycogen synthesis.

Key Points

Determine the existence of distinct molecular forms of UDPG-α-glucan transglucosylase and characterize the mechanisms governing their interconversion in skeletal muscle tissue.
Extracted and fractionated UDPG-α-glucan transglucosylase from dog skeletal muscle preparations.
Assayed enzyme activity across various fractions to examine kinetic behavior and interconversion between forms.
Identified two distinct forms of UDPG-α-glucan transglucosylase in canine skeletal muscle displaying differing regulatory profiles.
Demonstrated enzymatic interconversion between the two states, establishing a dynamic biochemical switch for regulating muscle glycogen synthesis.

Cite This Study

Rosell-Pérez et al. (1964) studied this question.

synapsesocial.com/papers/6a6fc7898031ec7bb1dbf1ad https://doi.org/10.1021/bi00889a014

View Full Paper

Ask AI

Bookmark