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December 31, 1893Proceedings of the Royal Society of LondonOpen Access

V. On the estimation of uric acid in urine: a new process by means of saturation with ammonium chloride

Frederick Gowland Hopkins

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Abstract

The process to be described depends upon the following facts:— 1. Ammonium urate is wholly insoluble in saturated solutions of ammonium chloride. 2. If solutions, such as urine, which contain the mixed urates of different bases be saturated with ammonium chloride, the large mass-influence of the latter ensures the rapid and complete conversion of all the uric acid into biurate of ammonium, which, in accordance with (1), is, pari passu, thrown out of solution

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Frederick Gowland Hopkins (1893) studied this question.

synapsesocial.com/papers/6a6fcdaa78a11c550e099320 https://doi.org/10.1098/rspl.1892.0055

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