Gamma radiation causes disturbances in energy metabolism, decreases in (Na/sup +/-K/sup +/)-ATPase, Mg/sup 2 +/-APTase activity, and increase in the degree of hemolysis in porcine erythrocytes. Our results indicated a contribution of exogenous free radicals in radiation damage to porcine erythrocytes. In the presence of biological and chemical radioprotectors a protective effect with respect to ATPase activity and energy metabolism was observed in the presence of catalase, histidine, glucose, and sulfhydryl compounds. It appears that radiation damage to porcine erythrocytes is due to the action of various radicals formed upon irradiation which react at different rates with various cell constituents.
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Jóźwiak et al. (1981) studied this question.
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