Why the study?
Does PTCA alter the coronary circulation levels of L-PGDS in patients with stable angina?
Population
Human autopsy specimens, patients with stable angina, and normal subjects without stenosis.
Comparison
Percutaneous transluminal coronary angioplasty vs Pre-PTCA levels and normal subjects without…
Design
Cohort
Follow-up
1 hour post-PTCA
Authors
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May indicate cardiac L-PGDS production in stable angina; leaves open its value as biomarker or target.
Does PTCA alter the coronary circulation levels of L-PGDS in patients with stable angina?
L-PGDS is expressed in the human heart and accumulates in the coronary circulation of patients with stable angina, with levels decreasing after PTCA.
Eguchi et al. (1997) studied this question.
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