Why the study?
Does 41.8 degrees C whole-body hyperthermia alter mood states in cancer patients?
Does 41.8 degrees C whole-body hyperthermia alter mood states in cancer patients?
Whole-body hyperthermia in cancer patients transiently increases fatigue but significantly improves depression up to 72 hours post-treatment.
Transient fatigue rise with depression improvement up to 72 h may occur; hypothesis-generating in cancer, needs RCTs before practice change.
Mood states of cancer patients were assessed pre- and post-41.8 degrees C whole-body hyperthermia using the Profile of Mood States questionnaire. Results demonstrated a statistically significant increase in fatigue associated with decreased vigour which returned to baseline values by 72 h. In contrast, a significant improvement in depression was evident through 72 h following treatment. The relationship of this result to earlier studies of WBH-induced beta-endorphin is discussed.
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Koltyn et al. (1992) studied this question.
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