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IN recent years it has become apparent that the syndrome called idiopathic thrombocytopenic purpura consists of a complex of disorders. This syndrome, as we have defined it,1 is characterized by thrombocytopenic purpura, a normal or increased number of megakaryocytes in the bone marrow and no apparent splenomegaly. Perhaps the most striking evidence that the disease represents a syndrome rather than a well defined entity comes from the diversity of clinical situations in which it occurs. It may be truly "idiopathic" in the present state of limited knowledge, but, on the other hand, an identical thrombocytopenic state may be related to . . .
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Dameshek et al. (1963) studied this question.
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