Goldenyne: O-tethered 1,6-enynes that contain a strained ring at the 3 position can cycloisomerize upon cationic gold(I) catalysis through a ring-expansion process. A two-step sequence allows the transformation of the cyclized compounds into ketomacrolactones, which are reminiscent of natural products.
No takes yet. Share an insight, caveat, or question.
Simonneau et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: