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April 25, 2000Proceedings of the National Academy of SciencesOpen Access

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor β signaling by targeting Smads to the ubiquitin–proteasome pathway

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JXJing XuNanchang UniversityLALiliana AttisanoUniversity of Toronto

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Xu et al. (2000) studied this question.

synapsesocial.com/papers/6a6ff370e5469ee92be0bef9https://doi.org/10.1073/pnas.97.9.4820
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Also Consider

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  1. 1TGF-β SIGNAL TRANSDUCTION1998 · 7,587 citations
  2. 2<i>DPC4</i> , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.11996 · 2,352 citations