Key result
Elevated platelet-to-albumin ratio strongly predicts diabetic nephropathy in type 2 diabetes.
Observational (n=180)
Aim: To evaluate whether platelet-to-albumin ratio (PAR) can predict diabetic nephropathy (DN) in type 2 diabetes mellitus (T2DM). Materials & methods: A total of 140 patients with T2DM and 40 healthy individuals were enrolled retrospectively. T2DM patients were divided into three groups based on the urinary albumin-to-creatinine ratio, PAR was compared and receiver operating characteristic curve was constructed to evaluate the predictive value of PAR in DN in T2DM. Results: There was a significant increase of PAR in DN among T2DM patients and PAR was positively correlated with serum creatinine, retinol-conjugated protein and β2-microglobulin. Moreover, PAR was a risk factor for DN in T2DM patients, which predicted DN in T2DM with high sensitivity and specificity. Conclusion: PAR can be a potential candidate to predict DN in T2DM.
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Cao et al. (2023) conducted an observational in Type 2 diabetes mellitus and diabetic nephropathy (n=180). Platelet-to-albumin ratio (PAR) was evaluated on Diabetic nephropathy.
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