Effects of Environment on Respiratory Function

Respiratory function of a random sample of a previously studied class of seminary students was evaluated once each week on 27 occasions between October and May in order to determine the relationship of variation in function with environmental factors. A statistical method is presented for systematic sorting of meaningful significant correlations. The best correlation was found between fraction of predicted functional residual capacity and ambient temperature. Although "spot" measurements (paper tape-soiling index) made a significant contribution, no meaningful relationship could be demonstrated for respiratory function and other measured air pollution or meteorological parameters. The significant environmental-respiratory function interaclions demonstrated occurred in some but not an subjects. Airway resistance levels in subjects with a history of asthma, but presently asymptomatic, were significantly higher, but there was no obvious difference in their relationship to the measured environmental factors.