Baseline T wave abnormalities, high lipoprotein (a), high BMI, and smoking in 50-year-old men predict the development of major abnormal Q/QS patterns 20 years later, which often occur without clinically recognized myocardial infarction.
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May flag long-term ECG risk in middle-aged men; hypothesis-generating and requires prospective validation before practice change.
Møller et al. (2006) studied this question.
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